Proofpoint has announced an expansion of its global partnership with Microsoft, leveraging Microsoft Azure’s AI capabilities and cloud infrastructure to enhance future developments in threat and data protection.
This expanded collaboration aims to strengthen Proofpoint’s human-centric security platform through Azure, leading to better threat detection, simplified operations, and improved risk management. This initiative is part of a broader strategy to deliver enhanced threat protection and data security on a global scale.
Darren Lee, Executive Vice President and General Manager, Threat Protection Group at Proofpoint, stated, “Human-centric security is about enabling the digital workspace. And for most of our enterprise customers, that digital workspace is Microsoft. Built on top of Microsoft Azure, we’re delivering advanced, preventive protection for the most important layer in the cybersecurity ecosystem —the human layer. We’re equipping organisations with the capabilities they need to reduce human risk at scale and thrive in their digital workspace.”
Kathleen Brown, Corporate Vice President, Americas Enterprise at Microsoft, commented, “Microsoft Azure is the cloud platform of choice for security vendors across the industry. Today’s announcement is a great example of how Azure provides powerful cloud infrastructure to help Microsoft and our partners meet our mutual customers’ evolving security requirements.”
By the end of the second quarter of 2025, Proofpoint plans to host its human-centric platform on Azure, incorporating Nexus intelligence technologies. These technologies utilize AI models and behavioral analysis to proactively identify and mitigate risks.
With the integration into Microsoft 365 via Azure, Proofpoint’s platform is designed to provide more effective solutions for managing contemporary threats while ensuring agility in digital environments. This includes improved email security, enhanced data protection, and increased efficiency with cost savings.
As part of this partnership, enhanced threat defense measures will be introduced, allowing the integration of Proofpoint’s Nexus threat intelligence into Microsoft Sentinel through Proofpoint Targeted Attack Protection SIEM APIs. This integration will benefit Microsoft Sentinel users by incorporating Proofpoint’s threat data, improving analytics, and enhancing XDR workflows, which will lead to quicker incident responses and better visibility of emerging threats.
The collaboration also extends advanced threat protection by integrating solutions like Proofpoint Adaptive Email DLP with Microsoft Purview and Proofpoint TAP with Microsoft Defender for Endpoint, which are already in use.
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